UKRI
Experimental medicine stage one
The questions, word limits and assessment criteria below are the funder’s own, taken from the published competition material. You still submit through their service; this is where the writing happens first.
11 questions, straight from the funder
Their word limits are on every box, counted live as you type, and what the assessor is told to look for sits beside it. All of that is free. The pre-sift check — every mechanical rule that rejects a proposal before anyone reads it, run over what you have written — comes with the pass.
Application questions
Q1 Summary
0 / 550 wordsIn plain English, provide a summary we can use to identify the most suitable experts to assess your application. We usually make this summary publicly available on external-facing websites, therefore do not include any confidential or sensitive information. Make it suitable for a variety of readers, for example: opinion-formers policymakers the public the wider research community
Q2 Keywords
0 / 10 wordsProvide up to five keywords that describe your application.
Q3 Related applications
0 / 1500 wordsIs this application a resubmission of a previous experimental medicine stage one or an invited resubmission of a stage two application? If yes, please outline the feedback received and the changes made in response to it.
What the assessor looks for
- this application differs from the previous application
- previous feedback has been considered and addressed
A filled dot only means your answer mentions that ground. It is not a judgement of how well.
Q4 New investigator applicants
0 / 10 wordsAre you applying as a new investigator?
Q5 Vision
0 / 550 wordsWhat are you hoping to achieve with your proposed work?
What the assessor looks for
- is of excellent quality and importance within or beyond the field(s) or area(s)
- has the potential to advance current understanding, or generate new knowledge, thinking or discovery within or beyond the field or area
- is timely given current trends, context, and needs
- impacts world-leading research, society, the economy, or the environment
- outline the current clinical challenge, healthcare burden or knowledge gap
- summarise the current state of understanding about the relevant mechanisms of disease
- identify the current gap in mechanistic understanding
- state the mechanistic hypothesis to be tested
- identify the potential direct or indirect benefits and who the beneficiaries might be
- if applicable, describe the route to patient benefit
A filled dot only means your answer mentions that ground. It is not a judgement of how well.
Q6 Intervention
0 / 275 wordsWhat is the planned intervention?
What the assessor looks for
- the type of intervention, which may include compound, biologic, psychological, physiological, vaccine or immune challenge
- relevant background information, including its established safety profile and use in other mechanistic studies
A filled dot only means your answer mentions that ground. It is not a judgement of how well.
Q7 Approach
0 / 2000 wordsHow are you going to deliver your proposed work?
What the assessor looks for
- project plan and milestones: 750 words
- methodology and experimental design: 750 words
- risk management: 300 words
- infrastructure and equipment: 200 words
A filled dot only means your answer mentions that ground. It is not a judgement of how well.
Q8 Reproducibility and statistical design
0 / 250 wordsHow will you ensure your proposed work is reliable, robust and reproducible?
Q9 Applicant and team capability to deliver
0 / 1800 wordsWhy are you the right individual or team to successfully deliver the proposed work?
What the assessor looks for
- the relevant experience ( appropriate to career stage ) to deliver the proposed work
- the right balance of skills and expertise to cover the proposed work
- the appropriate leadership and management skills to deliver the work and your approach to develop others
- contributed to developing a positive research environment and wider community
- 1,100 words to be used for Résumé for Research and Innovation (R4RI) modules (including references)
- 200 words to summarise the career stage of the core team (an example table will be provided within the Funding Service to assist you with your summary)
- 500 words for Additions, if necessary
- contributions to the generation of new ideas, tools, methodologies, or knowledge. This may include your previous funding and key outputs such as publications
- the development of others and maintenance of effective working relationships
- contributions to the wider research and innovation community
- contributions to broader research or innovation users and audiences and towards wider societal benefit, including public partnerships
- if you are applying as a new investigator, you need to make your leadership role clear and justify the team around you
A filled dot only means your answer mentions that ground. It is not a judgement of how well.
Q10 Project partners: letters (or emails) of support
0 / 10 wordsUpload a single PDF containing the letters or emails of support from each partner you named in the ‘Project partners’ section. These should be uploaded in English or Welsh only.
Q11 Ethics and responsible research and innovation (RRI)
What are the ethical and RRI considerations, implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.
What the assessor looks for
- the relevant ethical and RRI considerations, including both the research or topic area itself and the design and delivery of the project
- the wider implications of the proposed work, and how you will maximise the positive societal, environmental, and economic benefits arising from the project, while minimising unintended negative impacts, such as research misuse or accidental harm
- how you will manage these considerations throughout the lifecycle of the project
A filled dot only means your answer mentions that ground. It is not a judgement of how well.